Cyclic Anhydride Formation by BOC2O

Letter
    

Facile and Efficient Synthesis of Cyclic Anhydrides from Dicarboxylic Acids

 

 

Carine Robert^†, Frédéric de Montigny^†, and Christophe M. Thomas^*†

^† PSL Research University, CNRS - Chimie ParisTech, Institut de Recherche de Chimie Paris, 75005 Paris, France

ACS Catal., 2014, 4 (10), pp 3586–3589

DOI: 10.1021/cs501237p

Publication Date (Web): September 9, 2014

Copyright © 2014 American Chemical Society

*E-mail: christophe.thomas@chimie-paristech.fr.

 

Abstract

 

 

 

An efficient, high-yielding sustainable route to cyclic anhydrides from biorenewable and inexpensive dicarboxylic acids has been developed. Cyclic anhydrides were synthesized from dicarboxylic acids using a catalyst prepared in situ from MgCl₂ and dialkyl dicarbonates. This robust and cheap system operates under mild conditions to give cyclic anhydrides with high yield and selectivity.

 

Keywords:

catalysis; cyclic anhydride; cyclization; dicarboxylic acid; magnesium

Supporting Information

---

Full experimental details and characterization data for all new compounds are included in Supporting Information. This material is available free of charge via the Internet at http://pubs.acs.org.

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Received 21 August 2014

Published online 9 September 2014

Published in print 3 October 2014

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