are claimed as molecules that inhibit tau phosphorylation.
This approach to neurodegenerative disease is of interest because of the hypothesized role for tau in neuronal cell death.
Tau is an intracellular protein that stabilizes microtubules and helps regulate their function, for example in cell division.
Test compounds were studied for their ability to inhibit tau phosphorylation or inhibit α-synuclein in animals and in cell culture.
With these Indole drug segments in hand, the Rhodanines should be connected to 5-Cl-Tryptamines to produce New Nootropic Compounds based on the RDScafolds such as Eparlestat.
返信削除The Cyanophenyl Ring should be substituted with CYanoPYrazole(CYPY) Rings for Neurodegenerative Treatments. The CYPY Tactics for Nootropic Therapy.
返信削除SCAFOLD For AD.