糖化反応阻害剤＝糖トラップ化アミン＝メトフォルミン

 

Ｓｅｅ　Ｆｏｒ　Ｇｏｏｄ　Ｅｘａｍｐｌｅｓ；

 

 

http://ebn.arkray.co.jp/disciplines/glycation/ages-08/

Pleiotropiv Effects of Pitavastatin 2011

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376429/


and More;

Pitavastatin Pleiotropic Study

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387666/

Conclusions

Pitavastatin not only improved atherosis measured by IMT and the sclerosis measured by cIBS values, but also attenuated inflammation of plaques at the same site as measured by max SUV. The present study indicated that pitavastatin had a stronger effect on regression and stabilization of plaques in the thoracic aorta compared with a mild hydrophilic statin.

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Acknowledgements

This study was funded by a grant from Japan vascular disease research foundation, Kyoto, Japan.

Cilostazol & ROCK 2016

See As Recent Opinions;

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098914/

Simple Radical Metabolic Pathways for Anti-TB Drug & Others

 

Ｒａｄｉｃａｌ　Ｍｅｔａｂｏｌｉｃ　Ｐａｔｈｗａｙｓ

Ｆｏｒ　Ｉｓｏｎｉａｚｉｄ, Ｄｅｌａｍａｎｉｄ and Ｅｐａｌｒｅｓｔａｔ．

This Paper deals with the new radical metabolic patway
for two ant-TB drugs (Isoniazid and Delamanid) and one
ARI (aldose reductase inhibitor).

http://www.pnas.org/content/100/24/13881.full

Ｐｉｔａｖａｓｔａｔｉｎ　Ｗｏｒｋｓ　Ａｓ　ＲｈｏＡ

 

Ｉｎｖｅｒｓｅ　Ａｇｏｎｉｓｔ　Ｂｕｔ　Ｎｏｔ　ＧＰＣＲ１２０　Ｌｉｇａｎｄ．